The 53-year-old woman was rushed to hospital after emergency services were called to a two car crash on Dunnings Road in Point Cook, just after 11pm on Friday night.
“The Holden collided with another vehicle, a grey Volkswagen Golf travelling south on Boardwalk boulevard,” Victoria Police said in a statement.
“It’s alleged the driver of the Holden failed to stop fleeing the scene on foot.”
The 25-year-old driver and passenger allegedly left the woman in a critical condition.
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“Police located and arrested the driver of the Holden a short time later at his address,” police said.
“A 53-year-old Point Cook woman was taken to hospital with life-threatening-injuries.”
Investigations are on going.