A man has died in a motorcycle crash after a police pursuit in Sydney’s south-west.

Police attempted to stop a motorcycle rider travelling south on the Hume Highway at Liverpool about 2am today.

Police said when the rider failed to stop, they began to pursue him.

A man has died in a motorcycle crash after a police pursuit in Sydney's south-west.
A man has died in a motorcycle crash after a police pursuit in Sydney’s south-west. (Nine)

The pursuit was called off at Flowerdale Road due to safety concerns.

The rider crashed into a parked car on Flowerdale Road a short time later.

Paramedics were called to the scene and attempted to treat the rider.

A crime scene has been established, and a critical incident has been declared.

The Law Enforcement Conduct Commission will review the incident.

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