Major flood warnings have been issued for the Nicholson, Gregory and Leichhardt Rivers and the surrounding areas.
Burketown is expected to bear the brunt of the flood, with water levels expected to exceed the March 2011 record of 6.87m on Friday.
Flooding at Doomadgee has already hit record levels, peaking at 7.85m this morning.
Riversleigh flooding peaked at 18m, which is 12.5m above the official major flood level.
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The lower Flinders River region at Walkers Bend has also been issued with a major flood warning, with over 170mm of rain hitting the area in 24 hours.
The river peaked at 9.5m and is expected to remain at major flood levels until Friday as the region is hit by more rain and thunderstorms in the next few days.
The Cloncurry River has been issued a minor flood warning, with officials saying the river could reach 3m overnight.
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