A bus carrying wedding guests fell into the Indus River in northern Pakistan on Tuesday, killing at least 26 people, officials said.

It happened in the Gilgit Baltistan region as the bus was heading to Chakwal, a city in Punjab province, government spokesman Faizullah Faraq said.

He said so far only one woman had been found alive and was being treated at a hospital. Police said rescuers will resume searching for missing passengers on Wednesday.

Many are dead after a bus carrying wedding guests crashed into a river in Pakistan. (9News)

Police also said it was unclear what caused the crash, and officers were yet to record the lone survivor’s statement.

Pakistani President Asif Ali Zardari offered condolences and asked rescuers to expedite efforts to find missing passengers.

Road accidents are common in Pakistan due to poor infrastructure and disregard for traffic laws and safety standards. In August, 36 people were killed and dozens of others were injured in two separate bus crashes.

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