The crash occurred in Pine Lodge (pictured) east of Shepparton in rural Victoria

Four people have died after a car collided with a ute near the Victorian rural city of Shepparton.

The crash occurred about 4.45pm on Wednesday afternoon with the driver of the car being flown to hospital in a serious condition, while the driver of the ute suffered minor injuries.

Traffic has been halted at the site – an intersection in Pine Lodge just east of Shepparton – as emergency crews attend the scene. 

The crash occurred in Pine Lodge (pictured) east of Shepparton in rural Victoria

The crash occurred in Pine Lodge (pictured) east of Shepparton in rural Victoria

The crash occurred in Pine Lodge (pictured) east of Shepparton in rural Victoria 

The car was knocked off the road and has ended up in a paddock, with Victoria Police confirming four passengers perished.

The driver of the ute remained at the scene to assist emergency crews. 

Major Collision Investigation Unit detectives are being flown from Melbourne to investigate the scene and determine the cause of the crash. 

More to follow.